Notes

  1. Prescribe paracetamol with caution to people with severe renal impairment. Dose reduction might be required; liaise with the patient’s GMP to discuss.
  2. Prescribe NSAIDs with caution to people with mild to moderate renal impairment; avoid if possible (do not prescribe in severe renal impairment). Sodium and water retention may occur leading to a deterioration in renal function and, possibly renal failure.
    If the patient cannot avoid using an NSAID and has impaired renal function, monitoring of renal function is required 1–2 weeks after starting or increasing the dose of an NSAID. Liaise with the patient’s GMP to discuss.